Claire used to have the perfect life: she was married to Ethan and a son named Colton. But because of a rare disease that she has, it affected Colton and he dies at the age of eight. Ethan wants to try for another child, but Claire is afraid she will pass this on to another child. After several discussions, they decided to try IVF with Dr. Nash who Claire trusts and Ethan does not. Dr. Nash has been doing research with a renowned scientist named Jillian, but things are still in the early stages. Even though Ethan doesn't trust him and voices his concerns, Claire goes along with the procedure against her husband's wishes, which will result in the first baby created with three genetic parents.

Fast forward ten years and Claire and Nash are now raising their daughter named Abigail together, while Jillian is in prison when her unorthodox research methods are exposed. Jillian is out of prison, though, and she wants revenge on Claire and Nash. Will her warped mind after ten years of plotting wreck havoc on their lives? And will Abigail discover the truth about how she was born? Only time will tell. . . 

MOTHER KNOWS BEST is the first novel that I have read by Kira Peikoff. I can tell you that this will not be my last. It really is a thriller beyond words. As I was reading this novel I wondered if this could possibly happen, or maybe it already has. Peikoff's story takes you on a psychological thriller that combines love and sometimes a bad love. The deeper you get into this book, you will see what I mean. If you like thrillers, suspense, and even some romance, MOTHER KNOWS BEST is the book for you.