Samantha Trudeau is an N3 operative in a secret Neural division of the FBI. As an empath, a person who is able to use her psychic abilities to discern the truth just by skin on skin contact, she is a valuable weapon against crime. Her boss, Flinn Ford, found her at the age of 19 and kept her from going to prison for killing someone. Yet, Flinn has also run many tests on her over the years for personal gain.

Samantha is running for her life. Her co-worker and friend is murdered in front of her and she is shot in the shoulder. Bleeding and scared, Sam makes it to the family cabin in the mountains, during a storm. Weak from the gunshot, she collapses.

Mac Hunter has tried to drown his problems in alcohol. His good friends and co-workers, at a newspaper company, Charlie and Alex Trudeau, intervene and send him off to their cabin for a holiday. Mac arrives during the thunderstorm and finds Sam collapsed on the floor. He cleans her up and bandages her wounds. Her ID says she is someone else, but Mac knows she is Alex and Charlie's long-lost sister. The pictures in the cabin prove it. Sam asks Mac to cut a transmitter out of her back so Flinn cannot find her. However, she is unaware that by doing so, a drug is released into her system, which causes her to develop amnesia. Unable to remember her past, Sam and Mac find themselves on an adventure that may be their last.

Joyce Lamb wraps up her suspense trilogy about three psychic sisters with TRUE SHOT. The relationship between a well- trained operative and a man who only seems to be well- trained with words is lively. Her lack of trust, his natural instinct to protect women, and the feds who are always just one step behind them, provide sweet dialogue and continuous action. The scenes once Flinn captures Sam are graphic and disturbing and the culmination of the story is satisfying and complete.